Chemokine-enhanced DNA vaccination in cancer immunotherapy.

Authors

Olga Igoucheva, Thomas Jefferson UniversityFollow
Rebecca Jonas, Thomas Jefferson University
Vitali Alexeev, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

10-1-2013

Comments

This article has been peer reviewed. It was published in: OncoImmunology

Volume 2, Issue 10, October 2013, e26092.

The published version is available at DOI: 10.4161/onci.26092 . Copyright © Landes Bioscience

Abstract

We have demonstrated that priming of intratumoral and intradermal vaccination sites with chemokines enhances cytotoxic immune response against established neoplasms. Additional insights into the molecular mechanisms that underlie these findings and the optimization of such an approach may lead to the development of cost-effective and generic immunotherapeutic regimens against cancer.

Recommended Citation

Igoucheva, Olga; Jonas, Rebecca; and Alexeev, Vitali, "Chemokine-enhanced DNA vaccination in cancer immunotherapy." (2013). Department of Dermatology and Cutaneous Biology Faculty Papers. Paper 32.
https://jdc.jefferson.edu/dcbfp/32

PubMed ID

24251079