Manuscripts from 2015
Consequence of the tumor-associated conversion to cyclin D1b., Michael A Augello, Lisa D Berman-Booty, Richard Carr, Akihiro Yoshida, Jeffry L Dean, M J Schiewer, Felix Y Feng, Scott A Tomlins, Erhe Gao, Walter J Koch, Jeffrey L Benovic, John Alan Diehl, and Karen E Knudsen
Expression of Interferon Gamma by a Recombinant Rabies Virus Strongly Attenuates the Pathogenicity of the Virus via Induction of Type I Interferon., Darryll A Barkhouse; Samantha A Garcia; Emily K Bongiorno; Aurore Lebrun; Milosz Faber; and D Craig Hooper, PhD
ErbB3-ErbB2 Complexes as a Therapeutic Target in a Subset of Wild-type BRAF/NRAS Cutaneous Melanomas., Claudia Capparelli, Sheera Rosenbaum, Lisa D. Berman-Booty, Amel Salhi, Nadège Gaborit, Tingting Zhan, Inna Chervoneva, Jason Roszik, Scott E. Woodman, Michael A. Davies, Yulius Y. Setiady, Iman Osman, Yosef Yarden, and Andrew E. Aplin
Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis., Mathew C Casimiro, Gabriele Disante, Marco Crosariol, Emanuele Loro, William Dampier, Adam Ertel, Zuoren Yu, Elizabeth A Saria, Alexandros Papanikolaou, Z Li, Chenguang Wang, Sankar Addya, Michael P. Lisanti, Paolo Fortina, Robert D Cardiff, Aydin Tozeren, Erik S Knudsen, Andrew Arnold, and Richard Pestell
Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma., Hanyin Cheng, Mizue Terai, Ken Kageyama, Shinji Ozaki, Peter McCue, Takami Sato, and Andrew E. Aplin
The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module., Ke Chen, Kongming Wu, Xuanmao Jiao, Liping Wang, Xiaoming Ju, Min Wang, Gabriele Disante, Shaohua Xu, Qiong Wang, Kevin Li, Xin Sun, Chongwen Xu, Zhiping Li, Mathew C. Casimiro, Adam Ertel, Sankar Addya, Peter McCue, Michael P. Lisanti, Chenguang Wang, Richard J. Davis, Graeme Mardon, and Richard Pestell
Novel actions of next-generation taxanes benefit advanced stages of prostate cancer., Renée de Leeuw, Lisa D. Berman-Booty, Matthew J. Schiewer, Stephen J Ciment, Robert Den, Adam P. Dicker, William Kelly, Edouard J. Trabulsi, Costas D. Lallas, Leonard G. Gomella, and Karen E. Knudsen
Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function., Felix Y. Feng, Johann S. de Bono, Mark A. Rubin, and Karen E Knudsen
Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression., Irene Forno, Stefano Ferrero, Maria Veronica Russo, Giacomo Gazzano, Sara Giangiobbe, Emanuele Montanari, Alberto Del Nero, Bernardo Rocco, Giancarlo Albo, Lucia R Languino, Dario C Altieri, Valentina Vaira, and Silvano Bosari
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis., Jonathan F Goodwin, Vishal Kothari, Justin M Drake, Shuang Zhao, Emanuela Dylgjeri, Jeffry L. Dean, Matthew J. Schiewer, Christopher McNair, Jennifer K. Jones, Alvaro Aytes, Michael S. Magee, Adam E. Snook, Ziqi Zhu, Robert Den, Ruth C. Birbe, Leonard G. Gomella, Nicholas A. Graham, Ajay A. Vashisht, James A. Wohlschlegel, Thomas G. Graeber, R. Jeffrey Karnes, Mandeep Takhar, Elai Davicioni, Scott A. Tomlins, Cory Abate-Shen, Nima Sharifi, Owen N. Witte, Felix Y. Feng, and Karen E. Knudsen
Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia., Zhiyong Liao, Lei Gu, Jenny Vergalli, Samanta A. Mariani, Marco De Dominici, Ravi K. Lokareddy, Ayush Dagvadorj, Puranik Purushottamachar, Peter A. McCue, Edouard J. Trabulsi, Costas D. Lallas, Shilpa Gupta, Elyse Ellsworth, Shauna Blackmon, Adam Ertel, Paolo Fortina, Benjamin E. Leiby, Guanjun Xia, Hallgeir Rui, David T. Hoang, Leonard G Gomella, Gino Cingolani, Vincent Njar, Nagarajan Pattabiraman, Bruno Calabretta, and Marja T. Nevalainen
Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage., F Marampon, G L Gravina, Xiaoming Ju, A Vetuschi, R Sferra, Mathew C Casimiro, S Pompili, C Festuccia, A Colapietro, E Gaudio, E Di Cesare, V Tombolini, and Richard Pestell
Antibiotics for cancer therapy., Richard Pestell and Albert A Rizvanov
NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma., Yongping Shao, Kaitlyn Le, Hanyin Cheng, and Andrew E. Aplin
DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1., Xin Sun, Shou-Ching Tang, Chongwen Xu, Chenguang Wang, Sida Qin, Ning Du, Jian Liu, Yiwen Zhang, Xiang Li, Gang Luo, Jie Zhou, Fei Xu, and Hong Ren
Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism., Michele Tavecchio, Sofia Lisanti, Michael J Bennett, Lucia R Languino, and Dario C Altieri
The Broad Stroke of Hsp90 Inhibitors: Painting over the RAF Inhibitor Paradox., Michael J Vido and A E Aplin
RAC1 P29S regulates PD-L1 expression in melanoma., Ha Linh Vu, Sheera Rosenbaum, Timothy J. Purwin, Michael A. Davies, and Andrew E. Aplin
Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1., Xuhui Zhang, Hai Wu, Jason R. Dobson, Gillian Browne, Deli Hong, Jacqueline Akech, Lucia R. Languino, Gary S. Stein, and Jane B. Lian
Manuscripts from 2014
AR function in promoting metastatic prostate cancer., Michael A Augello, Robert B Den, and Karen E Knudsen
Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity., Giovanna Ferrari-Amorotti, Claudia Chiodoni, Fei Shen, Sara Cattelani, Angela Rachele Soliera, Gloria Manzotti, Giulia Grisendi, Massimo Dominici, Francesco Rivasi, Mario Paolo Colombo, Alessandro Fatatis, and Bruno Calabretta
Genomics into Healthcare: the 5th Pan Arab Human Genetics Conference and 2013 Golden Helix Symposium., Paolo Fortina, Najib Al Khaja, Mahmoud Taleb Al Ali, Abdul Rezzak Hamzeh, Pratibha Nair, Federico Innocenti, George P. Patrinos, and Larry J. Kricka
Hormone whodunit: clues for solving the case of intratumor androgen production., Karen E Knudsen
miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer., Yuan Li, Chunli Liang, Haizhong Ma, Qian Zhao, Ying Lu, Zhendong Xiang, Li Li, Jie Qin, Yihan Chen, William C Cho, Richard G Pestell, Li Liang, and Zuoren Yu
Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe., R Mu, Y-B Wang, M Wu, Y Yang, W Song, T Li, W-N Zhang, B Tan, A-L Li, N Wang, Q Xia, W-L Gong, Chenguang Wang, T Zhou, N Guo, Z-H Sang, and H-Y Li
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc., John R. Prensner, Wei Chen, Sumin Han, Matthew K. Iyer, Qi Cao, Vishal Kothari, Joseph R. Evans, Karen E. Knudsen, Michelle T. Paulsen, Mats Ljungman, Theodore S. Lawrence, Arul M. Chinnaiyan, and Felix Y. Feng
Single nucleotide polymorphism of SREBF-1 gene associated with an increased risk of endometrial cancer in Chinese women., Chun-Ping Qiu, Qing-Tao Lv, Samina Dongol, Chenguang Wang, and Jie Jiang
The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness., Chellappagounder Thangavel; Ettickan Boopathi; Steve Ciment; Yi Liu; Raymond O'Neill; Ankur Sharma; Steve B McMahon; Hestia Mellert; Sankar Addya; Adam Ertel; Ruth Birbe; Paolo Fortina; Adam Dicker MD, PhD; Karen E Knudsen; and Robert Den MD
Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells., Lifeng Tian, Chenguang Wang, Fred K Hagen, Michael Gormley, Sankar Addya, Raymond Soccio, Mathew C Casimiro, Jie Zhou, Michael J Powell, Ping Xu, Haiteng Deng, Anthony A Sauve, and Richard Pestell
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma., Ha Linh Vu and A E Aplin
CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling., Tao Wang, Shuiming Guo, Zhuo Liu, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Xiaming Liu, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Shaohua Xu, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Liping Wang, Kongming Wu, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer., Tao Wang, Zhuo Liu, Shuiming Guo, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Shaohua Xu, Liping Wang, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
The retinoblastoma tumor suppressor pathway modulates the invasiveness of ErbB2-positive breast cancer., A K Witkiewicz; D W Cox; D Rivadeneira; Adam Ertel; Paolo Fortina; Gordon Schwartz, MD, MBA, FACS; and E S Knudsen
miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1., Zuoren Yu, Zengguang Xu, Gabriele Disante, Jennifer Wright, Min Wang, Yuan Li, Qian Zhao, Tao Ren, Xiaoming Ju, Ellen Gutman, Guangxue Wang, Sankar Addya, Tieyan Li, Zhendong Xiang, Chenguang Wang, Xiongfei Yang, Xiaolai Yang, and Richard Pestell
Association of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case-control study., Jie Zhang, Deyang Li, Falin Qu, Yibing Chen, Gang Li, Hequn Jiang, Xiaojun Huang, Hushan Yang, and Jinliang Xing
Manuscripts from 2013
Cyclin D1 determines estrogen signaling in the mammary gland in vivo., Mathew C Casimiro, Chenguang Wang, Z Li, Gabriele Disante, Nicole E Willmart, Sankar Addya, Lei Chen, Yang Liu, Michael P. Lisanti, and Richard Pestell
Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer., Ke Chen, Kongming Wu, Michael Gormley, Adam Ertel, Jing Wang, Wei Zhang, Jie Zhou, Gabriele Disante, Zhiping Li, Hallgeir Rui, Andrew A Quong, Steven B McMahon, Haiteng Deng, Michael P Lisanti, Chenguang Wang, and Richard G Pestell
Targeting cell cycle and hormone receptor pathways in cancer., C E S Comstock; M A Augello; J F Goodwin; R de Leeuw; M J Schiewer; W F Ostrander; R A Burkhart; A K McClendon; Peter McCue; Edouard J. Trabulsi; Costas D. Lallas; Leonard G Gomella, MD; M M Centenera; Jonathan Brody, MD; L M Butler; W D Tilley; and K E Knudsen, PhD
Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs., Clement W Gnanadurai, Ming Zhou, Wenqi He, Christina M Leyson, Chien-Tsun Huang, Gregory Salyards, Stephen B Harvey, Zhenhai Chen, Biao He, Yang Yang, D C Hooper, Berhnard Dietzchold, and Zhen F Fu
A STATement on vemurafenib-resistant melanoma., Edward J Hartsough and A E Aplin
A TH1 immune response efficiently clears rabies virus from the CNS in the absence of inflammation, Aurore Lebrun, Rhonda Kean, Jianwei Li, and Douglas Craig Hooper
Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibody., Jeong-Hwan Lee, Da-Young Park, Kyung-Jin Lee, Young-Kwan Kim, Yang-Kang So, Jae-Sung Ryu, Seung-Han Oh, Yeon-Soo Han, Kinarm Ko, Young-Kug Choo, Sung-Joo Park, Robert Brodzik, Kyoung-Ki Lee, Doo-Byoung Oh, Kyung-A Hwang, Hilary Koprowski, Yong Seong Lee, and Kisung Ko
IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels., Aejaz Sayeed, Carmine Fedele, Marco Trerotola, Kirat K Ganguly, and Lucia R Languino
Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver., Jonathan Schug, Lindsay B McKenna, Gabriel Walton, Nicholas Hand, Sarmistha Mukherjee, Kow Essuman, Zhongjie Shi, Yan Gao, Karen Markley, Momo Nakagawa, Vasumathi Kameswaran, Anastassios Vourekas, Joshua R Friedman, Klaus H Kaestner, and Linda E Greenbaum
Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity., Duanwen Shen, Mingfeng Bai, Rui Tang, Baogang Xu, Xiaoming Ju, Richard Pestell, and Samuel Achilefu
Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells., Ashley L Wilson, Randy S Schrecengost, Michael S Guerrero, Keena S Thomas, and Amy H Bouton
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment., Hong Zhou, Suhendan Ekmekcioglu, John W Marks, Khalid A Mohamedali, Kaushal Asrani, Keeley K Phillips, Sharron A N Brown, Emily Cheng, Michele B Weiss, Walter N Hittelman, Nhan L Tran, Hideo Yagita, Jeffrey A Winkles, and Michael G Rosenblum
Manuscripts from 2012
Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells., K J Basile, E V Abel, and A E Aplin
Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration., Franco Capozza, Casey Trimmer, Remedios Castello-Cros, Sanjay Katiyar, Diana Whitaker-Menezes, Antonia Follenzi, Marco Crosariol, Gemma Llaverias, Federica Sotgia, Richard G Pestell, and Michael P Lisanti
Cyclin d1 induces chromosomal instability., Mathew C Casimiro and Richard Pestell
Aleuria Aurantia Lectin (AAL)-reactive immunoglobulin G rapidly appears in sera of animals following antigen exposure., Songming Chen, Chen Lu, Hongbo Gu, Anand Mehta, Jianwei Li, Patrick B Romano, David Horn, D Craig Hooper, Carthene R Bazemore-Walker, and Timothy Block
Aleuria Aurantia Lectin (AAL)-Reactive Immunoglobulin G Rapidly Appears in Sera of Animals following Antigen Exposure., Songming Chen, Chen Lu, Hongbo Gu, Anand Mehta, Jianwei Li, Patrick B Romano, David Horn, D Craig Hooper, Carthene R Bazemore-Walker, and Timothy Block
Inflammatory signaling compromises cell responses to interferon alpha., W-C Huangfu, J Qian, C Liu, J Liu, A E Lokshin, D P Baker, H Rui, and S Y Fuchs
GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation., Jobin K John, Kim H T Paraiso, Vito W Rebecca, Liliana P Cantini, Ethan V Abel, Nicholas Pagano, Eric Meggers, Rahel Mathew, Clemens Krepler, Victoria Izumi, Bin Fang, John M Koomen, Jane L Messina, Meenhard Herlyn, and Keiran S M Smalley
Initial experience with Imacor hTEE-guided management of patients following transplant and mechanical circulatory support., Christopher Kang, Hitoshi Hirose, Harold Hasting, and
Cyclin D1 goes metabolic: dual functions of cyclin D1 in regulating lipogenesis., Karen E Knudsen
Successful management of bleeding complications in patients supported with extracorporeal membrane oxygenation with primary respiratory failure., K Lamb, Sw Cowan, N Evans, H Pitcher, T Moritz, M Lazar, H Hirose, and Nc Cavarocchi
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer., M P Myklebust, Z Li, T H Tran, H Rui, E S Knudsen, H Elsaleh, Ø Fluge, B Vonen, H E Myrvold, S Leh, K M Tveit, R G Pestell, and O Dahl
Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia., Felipe E Pedroso, Paul B Spalding, Michael C Cheung, Relin Yang, Juan C Gutierrez, Andrea Bonetto, Rui Zhan, Ho Lam Chan, Nicholas Namias, Leonidas G Koniaris, and Teresa A Zimmers
ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity., Y Shao and A E Aplin
Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity., Trisha R Stankiewicz, F Alexandra Loucks, Emily K Schroeder, Marja T Nevalainen, Kenneth L Tyler, Klaus Aktories, Ron J Bouchard, and Daniel A Linseman
Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis., Marco Trerotola, Jing Li, Saverio Alberti, and Lucia R. Languino
Small non-coding RNAs govern mammary gland tumorigenesis., Zuoren Yu and Richard Pestell
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1., Xiaoping Zhao, Daorong Feng, Qun Wang, Arian Abdulla, Xiao-Jun Xie, Jie Zhou, Yan Sun, Ellen S Yang, Lu-Ping Liu, Bhavapriya Vaitheesvaran, Lauren Bridges, Irwin J Kurland, Randy Strich, Jian-Quan Ni, Chenguang Wang, Johan Ericsson, Jeffrey E Pessin, Jun-Yuan Ji, and Fajun Yang
Manuscripts from 2011
Mechanisms of resistance to RAF inhibitors in melanoma., A E Aplin, Fred M Kaplan, and Yongping Shao
Tissue-specific regulation of mouse microRNA genes in endoderm-derived tissues., Yan Gao, Jonathan Schug, Lindsay B McKenna, John Le Lay, Klaus H Kaestner, and Linda E Greenbaum
An integrated framework to model cellular phenotype as a component of biochemical networks., Michael Gormley, Viswanadha U Akella, Judy N Quong, and Andrew A Quong
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease., B H Kang, M Tavecchio, H L Goel, C-C Hsieh, D S Garlick, C M Raskett, J B Lian, G S Stein, L R Languino, and D C Altieri
Manuscripts from 2010
Bimodal gene expression and biomarker discovery., Adam Ertel
C-jun inhibits mammary apoptosis in vivo., Sanjay Katiyar, Mathew C Casimiro, Luis Dettin, Xiaoming Ju, Erwin F Wagner, Hirokazu Tanaka, and Richard Pestell
Differential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell model., A Kathleen McClendon, Jeffry L Dean, Adam Ertel, and Erik S Knudsen
Manuscripts from 2009
High adsorption rate is detrimental to bacteriophage fitness in a biofilm-like environment., Romain Gallet, Yongping Shao, and Ing-Nang Wang
The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system., D Craig Hooper, Timothy W Phares, Marzena J Fabis, and Anirban Roy
Plant Vaccines: An Immunological Perspective., Douglas C. Hooper
STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells., Zsuzsanna S Nagy, Matthew J LeBaron, Jeremy A Ross, Abhisek Mitra, Hallgeir Rui, and Robert A Kirken
Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer., M J Schiewer, L M Morey, C J Burd, Y Liu, Diane E Merry, S-M Ho, and Karen E Knudsen
Immunological assessment of plant-derived avian flu H5/HA1 variants., S Spitsin, V Andrianov, N Pogrebnyak, Y Smirnov, N Borisjuk, C Portocarrero, V Veguilla, H Koprowski, and M Golovkin
Stromal Caveolin-1 Levels Predict Early Ductal Carcinoma in Situ Progression to Invasive Breast Carcinoma, A. K. Witkiewicz, A. Dasgupta, G. F. Schwartz, KH H. Nguyen, H. R. Rui, and M. P. Lisanti
Manuscripts from 2008
Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo, Ayush Dagbadorj, Robert A. Kirken, Benjamin Leiby, James Karras, and Marja T. Nevalainen
A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors., Shengwen Calvin Li and William Gunter Loudon
Alternate cyclin D1 mRNA splicing modulates P27KlP1 binding and cell migration, Zhiping Li, Chenguang Wang, Xuanmao Jiao, Sanjay Katiyar, Mathew C. Casimiro, George C. Prendergast, Michael J. Powell, and Richard G. Pestell
Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB., Francesco Marampon, Mathew C Casimiro, Maofu Fu, Michael J Powell, Vladimir M Popov, Jaime Lindsay, Bianca M Zani, Carmela Ciccarelli, Genichi Watanabe, Richard J Lee, and Richard G Pestell
Immune Evasion by Rabies Viruses through the Maintenance of Blood-Brain Barrier Integrity., Anirban Roy and Douglas C. Hooper
Manuscripts from 2007
Plant-derived EpCAM antigen induces protective anti-cancer response., Robert Brodzik, Sergei Spitsin, Max Golovkin, Katarzyna Bandurska, Carla Portocarrero, Monika Okulicz, Zenon Steplewski, and Hilary Koprowski
Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway., Ayush Dagvadorj, Sean Collins, Jean-Baptiste Jomain, Junaid Abdulghani, James Karras, Tobias Zellweger, Hongzhen Li, Martti Nurmi, Kalle Alanen, Tuomas Mirtti, Tapio Visakorpi, Lukas Bubendorf, Vincent Goffin, and Marja T Nevalainen
Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression., Dolores Di Vizio, Federica Sotgia, Terence M Williams, Ghada S Hassan, Franco Capozza, Philippe G Frank, Richard G Pestell, Massimo Loda, Michael R Freeman, and Michael P Lisanti
Smallpox subunit vaccine produced in Planta confers protection in mice, Maxim Golovkin, Sergei Spitsin, Vyacheslav Andrianov, Yuriy Smirnov, Yuhong Xiao, Natalia Pogrebnyak, Karen Markley, Robert Brodzik, Yuri Gleba, Stuart N Isaacs, and Hilary Koprowski
Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor, Sanjay Katiyar, Xuanmao Jiao, Erwin Wagner, Michael P. Lisanti, and Richard G. Pestell
Stabilization of SMAR1 mRNA by PGA2 involves a stem loop structure in the 5' UTR, Lakshminarasimhan Pavritha, Shravanti Rampalli, Surajit Sinha, Kadreppa Sreenath, Richard G. Pestell, and Samit Chattopadhyay
The functional significance of nuclear receptor acetylation., Vladimir M. Popov, Chenguang Wang, L . Andrew Shirley, Anne Rosenberg, Shengwen Li, Marja Nevalainen, Maofu Fu, and Richard G. Pestell
Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells, Bin Shi, Laura Sepp-Lorenzino, Marco Prisco, Peter Linsley, Tiziana deAngelis, and Renato Baserga
DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells, Kumaran Sundaram, Santhosh K. Mani, Kazuyuki Kitatani, Kongming Wu, Richard G. Pestell, and Sakamuri V. Reddy
Acetylation in nuclear receptor signaling and the role of sirtuins, Chenguang Wang, Michael J. Powell, Vladimir M. Popov, and Richard G. Pestell
Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation, James R. Whittle, Michael J. Powell, Vladimir M. Popov, L. Andrew Shirley, Chenguang Wang, and Richard G. Pestell
Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth, Kongming Wu, Manran Liu, Anping Li, Howard Donninger, Mahadev Rao, Xuanmao Jiao, Michael P. Lisanti, Ales Cvekl, Michael Birrer, and Richard G. Pestell
Manuscripts from 2006
Role of caveolin-1 in the regulation of the vascular shear stress response, Philippe G. Frank and Michael P. Lisanti
Epigenetics and the estrogen receptor, Jennifer E. Leader, Chenuang Wang, Vladimir M. Popov, Maofu Fu, and Richard G. Pestell
Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function., Chenguang Wang, Zhiping Li, Yinan Lu, Runlei Du, Sanjay Katiyar, Jianguo Yang, Maofu Fu, Jennifer E Leader, Andrew Quong, Phyllis M Novikoff, and Richard Pestell
