Consistent Surgeon Evaluations of Three-Dimensional Rendering of PET/CT Scans of the Abdomen of a Patient with a Ductal Pancreatic Mass.

Authors

Matthew E Wampole, Department of Biochemistry and Molecular Biology, Thomas Jefferson UniversityFollow
John C Kairys, Department of Surgery, Thomas Jefferson University; Kimmel Cancer Center, Thomas Jefferson UniversityFollow
Edith P Mitchell, Department of Medical Oncology, Thomas Jefferson University; Kimmel Cancer Center, Thomas Jefferson UniversityFollow
Martha L Ankeny, Academic and Instructional Support and Resources, Thomas Jefferson UniversityFollow
Mathew L Thakur, Department of Radiology, Thomas Jefferson University; Kimmel Cancer Center, Thomas Jefferson UniversityFollow
Eric Wickstrom, Department of Biochemistry and Molecular Biology, Thomas Jefferson University; Kimmel Cancer Center, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

9-24-2013

Comments

This article has been peer reviewed and is published in PLoS One.

Volume 8, Issue 9, 24 September 2013, Article numbere75237.

The published version is available at DOI: 10.1371/journal.pone.0075237. © 2013 Wampole et al.

Abstract

Two-dimensional (2D) positron emission tomography (PET) and computed tomography (CT) are used for diagnosis and evaluation of cancer patients, requiring surgeons to look through multiple planar images to comprehend the tumor and surrounding tissues. We hypothesized that experienced surgeons would consistently evaluate three-dimensional (3D) presentation of CT images overlaid with PET images when preparing for a procedure. We recruited six Jefferson surgeons to evaluate the accuracy, usefulness, and applicability of 3D renderings of the organs surrounding a malignant pancreas prior to surgery. PET/CT and contrast-enhanced CT abdominal scans of a patient with a ductal pancreatic mass were segmented into 3D surface renderings, followed by co-registration. Version A used only the PET/CT image, while version B used the contrast-enhanced CT scans co-registered with the PET images. The six surgeons answered 15 questions covering a) the ease of use and accuracy of models, b) how these models, with/without PET, changed their understanding of the tumor, and c) what are the best applications of the 3D visualization, on a scale of 1 to 5. The six evaluations revealed a statistically significant improvement from version A (score 3.6±0.5) to version B (score 4.4±0.4). A paired-samples t-test yielded t(14) = -8.964, p

Recommended Citation

Wampole, Matthew E; Kairys, John C; Mitchell, Edith P; Ankeny, Martha L; Thakur, Mathew L; and Wickstrom, Eric, "Consistent Surgeon Evaluations of Three-Dimensional Rendering of PET/CT Scans of the Abdomen of a Patient with a Ductal Pancreatic Mass." (2013). Department of Biochemistry and Molecular Biology Faculty Papers. Paper 59.
https://jdc.jefferson.edu/bmpfp/59

PubMed ID

24086475