Aminoacylation of tRNA is the cellular process for providing aminoacyl donors for the ribosome synthesis of polypeptides. New research highlights an unexpected structural overlap between enzymes involved in this process and those involved in the biosynthesis of cyclodipeptides, an important class of bioactive molecules.
Recommended CitationLahoud, Georges and Hou, Ya-Ming, "Biosynthesis: A new (old) way of hijacking tRNA." (2010). Department of Biochemistry and Molecular Biology Faculty Papers. Paper 21.